Drug
Varicella-Zoster Immune Glob
Pronounced
"VAR-i-SEL-a ZOS-ter i-MUNE GLOB-ue-lin"
Uses
This medication is used to help provide protection (antibodies) against a certain virus infection (varicella zoster) commonly known as chickenpox. It is used by certain people who have not been vaccinated or had the infection before and have had recent contact with someone infected with chickenpox. This medication is made from healthy human blood that has high levels of a certain substance (varicella zoster antibodies) which helps fight the infection.
Routine vaccination is usually the best way to protect against infection.
Warning
This medication may rarely cause serious problems from blood clots (such as heart attack, stroke, blood clots in the lungs or legs). You may be at increased risk for blood clots if you are an older adult, are severely dehydrated, have a catheter in a vein close to your heart for administering medications, or have a history of blood clots, heart/blood vessel disease, heart failure, stroke, or if you are immobile (such as on very long plane flights or being bedridden). If you use estrogen-containing products, these may also increase your risk. Before receiving this medication, if you have any of these conditions report them to your doctor or pharmacist.
To decrease the risk of serious blood clots, drink enough fluids to make sure you are not dehydrated before receiving this medication. Get medical help right away if any of these symptoms occur: shortness of breath/rapid breathing, chest/jaw/left arm pain, unusual sweating, confusion, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, sudden/severe headaches, trouble speaking, weakness on one side of the body, or sudden vision changes.
How to Use This Medication
This medication is usually given by injection into a muscle by a health care professional. Adults and children usually receive the injection in the upper arm, and infants receive it in the upper thigh. Large doses (more than 3 milliliters) should be divided into 2 or more injections and given at separate injection sites. Certain brands of this medication may be injected into a vein. The dosage and schedule of injections depend on your medical condition, weight, and response to treatment.
This medication is given as soon as possible after you have had contact with (been exposed to) someone with chickenpox. If you wait too long after being exposed, the medication may not be effective. Not everyone who is exposed to this infection should receive varicella zoster immune globulin. Discuss the risks and benefits with your doctor.