Drug
Carbidopa/Levodopa
Pronounced
"car-beh-DOE-puh/lee-voh-DOE-puh"
Uses
This product is used to treat symptoms of Parkinson's disease (such as shakiness, stiffness, difficulty moving). It is used when the usual medications taken by mouth for Parkinson's disease are not effective. Parkinson's disease is thought to be caused by too little of a naturally occurring substance (dopamine) in the brain. Levodopa changes into dopamine in the brain, helping to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter the brain. Carbidopa can also reduce some of levodopa's side effects such as nausea and vomiting.
How to Use This Medication
Read the Patient Information Leaflet if available from your pharmacist before you start using this product and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication is given as a continuous infusion into the small intestine using an infusion pump. It is given throughout the day, usually stopping at bedtime. At bedtime, take your dose of carbidopa/levodopa tablets by mouth as directed. This medication can only be prescribed by doctors who have completed a special program which explains the risks, benefits, and use of this product. When you first start using this medication, it is given through a tube through the nose into the small intestine. After a few days, if the doctor decides that this product is right for you, then the medication will be given through a tube through the abdomen into the small intestine. The tube through the abdomen will require surgery.
Follow all instructions from your health care professional about how to properly use and prepare this medication and the infusion pump. The cassettes containing the medication should not be used longer than 16 hours or re-used. Learn how to properly care for the tube insertion site and how to avoid infection. Also learn how to store and discard medical supplies safely. If you have any questions about the use of this medication or the infusion pump, consult your health care professional.
The dosage is based on your medical condition and response to treatment. Your daily dose is made up of a morning dose, a continuous dose, and extra doses. An extra dose is a small dose of this medication that can be given as needed during the day to treat sudden "off" symptoms.
It is best to avoid a high-protein diet (it decreases the amount of levodopa that your body takes in) during treatment, unless directed otherwise by your doctor. Separate your dose of this medication by as many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your doctor or pharmacist for more details.
Do not stop using this medication without consulting your doctor. Some conditions may become worse when this medication is suddenly stopped. Also, if you suddenly stop using this medication, you may have withdrawal symptoms (such as anxiety, depression, confusion, fever, muscle stiffness). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used this medication for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.
Tell your doctor if your condition does not get better or if it gets worse, or if you need more than 5 extra doses of the medication per day.